The Payload Operations Integration Center is responsible for NASA’s on board science operations for the International Space Station (ISS), and is in operation 24 hours a day, seven days a week at the Marshall Space Flight Center. The Payload Operations Center communicates with the astronauts on board the ISS on a daily basis and can remotely operate on-board science and technology experiments. There is a viewing area at Marshall where visitors can observe the control room operations. The Center also develops plans each day to help crewmembers make the best use of their time and resources on board, so they can accomplish their important research related to life science, fluid physics and materials science. Human life sciences experiments conducted on board the ISS are particularly critical to NASA’s preparations for future human space travel.